以中药当归细粉为原料,采用高速离心剪切粉碎机将其制备成纳米当归悬浮液,并通过ZetaPALS光散射粒度分布仪、光学显微镜、扫描电镜等测试方法对当归粉末进行表征。采用高效液相色谱(HPLC)对当归指标成分阿魏酸在超细粉碎前后的提取量进行测定。实验结果表明超细粉碎后当归颗粒平均粒径为76.5nm,并且分布均匀。大部分细胞壁和细胞膜被破碎。对于相同的提取时间,纳米当归的阿魏酸提取量比当归细粉增加了12.95%。

Influence of Nano Pulverization on Structure and Extraction Percent of AngelicaMA Pei-yan~1,2 ,FU Zheng-yi1,SU Yan-li1 (1.State Key Lab of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology, Wuhan 430070,China;2.School of Sciences, Wuhan University of Technology, Wuhan 430070,China)The nano particles of angelica were prepared by high-speed centrifugal sheering (HSCS) pulverizer. The particles were characterized by ZetaPALS light scattering granulometric analyzer, optical microscope and SEM. HPLC was employed to determine the content of ferulic acid, which is the indes ingredient of angelica. Experimental results showed that the average size of solid particle was 76.5 nm after nano-pulverization. The great majority of the plant cell was broken. After nano-pulverization, extraction percent of ferulic acid was increased by 12.95%angelica; nano particles; HPLC; microscopic characteristics